Medications and Dementia Risk

Medications That Increase Dementia Risk

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Several classes of medications have been linked to an increased risk of dementia. This information is based on recent research and is crucial for understanding potential risks associated with certain drug treatments. It's important to note that these are associations, and not all individuals taking these medications will develop dementia. However, the increased risk warrants careful consideration and discussion with healthcare providers.

The following drug classes have been identified as potentially increasing the risk of dementia:

• Anticholinergics: These medications, often used to treat conditions like allergies (e.g., Benadryl) and overactive bladder (e.g., Oxybutynin), have been associated with a 50-60% increased risk of dementia.[1]
• Benzodiazepines: Commonly prescribed for anxiety and insomnia (e.g., Xanax, Valium), long-term use of benzodiazepines has been linked to a 40-50% increased risk of dementia.[1]
• Proton Pump Inhibitors (PPIs): Used to reduce stomach acid (e.g., Omeprazole, Nexium), PPIs have shown a 30-44% increased risk of dementia with use for more than 3 years. This finding was published in Neurology in 2023.[1]
• Antipsychotics: Medications used to treat psychiatric conditions (e.g., Seroquel, Risperdal) have been associated with up to a 70% increased risk of dementia.[1]

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