Here's an analysis of cannabis use in Multiple Sclerosis (MS), based on the provided information, focusing on scientific evidence and applications.

Scientific Evidence

The use of cannabis in managing MS symptoms has been a subject of ongoing research. Several studies, including those published between 2023 and 2025, provide insights into its potential benefits.

According to www.iAsk.Ai - Ask AI:

Pain & Spasticity

One of the primary areas of investigation is the impact of cannabis on pain and spasticity, common symptoms of MS. A 2024 review highlighted the efficacy of Nabiximols, a 1:1 THC:CBD spray, in reducing spasticity. The review indicated a 30–40% reduction in spasticity with the use of Nabiximols.[1] Furthermore, CBD's mechanism of action involves modulating TRPV1 receptors, which contributes to easing neuropathic pain associated with MS.[1]

Neuroprotection

Research also explores the potential neuroprotective effects of cannabis. Animal studies conducted between 2023 and 2025 have shown promising results. These studies suggest that combinations of THC and CBD can help preserve myelin and reduce neuroinflammation.[1]

Cognitive & Mood Benefits

Beyond physical symptoms, cannabis is being studied for its effects on cognitive function and mood. A 2024 study indicated that low-dose THC improved processing speed in a significant portion of MS patients. Specifically, the study showed improvement in processing speed in 60% of MS patients.[1] Additionally, a 2023 trial demonstrated that CBD could lower anxiety and depression scores in patients with MS.[1] Recent findings from 2025 suggest that cannabis may also improve sleep quality. The 2025 study indicated that cannabis improved REM sleep by 20%.[1]

Answer Provided by iAsk.ai – Ask AI.